The difference between a node-locked and a floating license

MelanieTM  supports both node-locked and floating (network) licenses. The following figure illustrates the two options. Node-locked license A node-locked license is locked to a specific computer. MelanieTM will only be able to run in fully functional mode on that computer. If you choose the node-locked license option: To obtain the purchased license, provide the Host ID of the computer on which you will run MelanieTM . Install MelanieTM  on the computer for which you provided the Host ID (with administrative privileges). Place […]

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How does normalization work in MelanieTM?

Why is normalization needed? 2D gel electrophoresis experiments typically aim at comparing different samples in order to identify protein expression changes that are characteristic of those samples. Nevertheless, relevant expression changes are often obscured by systematic experimental variation such as: Differences in sample preparation (inconsistent amounts of starting material, variations in reagents or protocols, pipetting errors) Differences in sample loading (pipetting errors, sample loss during gel loading) Differences in staining/labeling (inconsistent staining times, differences in labeling efficiency between CyDyes) Differences in image […]

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